Resistance to endocrine-based therapy remains a challenge in hormone receptor–positive (HR+)/human epidermal growth factor receptor 2–negative (HER......READ MORE
Endocrine therapy remains the foundational treatment for patients with hormone receptor–positive (HR+)/human epidermal growth factor receptor 2–neg......READ MORE
An increased understanding of the mechanisms of resistance is leading to advances in the treatment of patients whose breast cancer progresses follo......READ MORE
Our understanding of the genetic and molecular alterations associated with hormone receptor–positive (HR+)/human epidermal growth factor receptor 2......READ MORE
Gene expression profiling is an emerging tool to help guide treatment decisions in patients with breast cancer. In particular, it has been used to ......READ MORE
Estrogen receptor (ER) expression remains the most important predictive biomarker of response to endocrine therapy in hormone receptor–positive (HR......READ MORE