HR-Positive HER2-Negative Breast Cancer

patient care perspectives

by Joseph A. Sparano, MD, FACP

Endocrine therapy remains the foundational treatment for patients with hormone receptor–positive (HR+)/human epidermal growth factor receptor 2–neg......READ MORE

patient care perspectives

by Matthew P. Goetz, MD

An increased understanding of the mechanisms of resistance is leading to advances in the treatment of patients whose breast cancer progresses follo......READ MORE

clinical topic updates

by Matthew P. Goetz, MD

Our understanding of the genetic and molecular alterations associated with hormone receptor–positive (HR+)/human epidermal growth factor receptor 2......READ MORE

clinical topic updates

by Matthew P. Goetz, MD

Gene expression profiling is an emerging tool to help guide treatment decisions in patients with breast cancer. In particular, it has been used to ......READ MORE

clinical topic updates

by Matthew P. Goetz, MD

Estrogen receptor (ER) expression remains the most important predictive biomarker of response to endocrine therapy in hormone receptor–positive (HR......READ MORE