Chronic Myeloid Leukemia

clinical topic updates

by Neil P. Shah, MD, PhD

The use of quantitative real-time polymerase chain reaction (qRT-PCR) to test for BCR-ABL1 transcript levels in chronic myeloid leukemia (CML) is t......READ MORE

clinical topic updates

by Gabriela S. Hobbs, MD

For some—but not all—patients with chronic myeloid leukemia (CML), tyrosine kinase inhibitor (TKI) therapy produces deep remissions with immune res......READ MORE

clinical topic updates

by Mark J. Levis, MD, PhD

Tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic myeloid leukemia (CML) to such an extent that this once-lethal disea......READ MORE

clinical topic updates

by Gabriela S. Hobbs, MD

Although upfront testing with next-generation sequencing (NGS) for BCR-ABL1 kinase domain mutations is not currently standard, the science of mutat......READ MORE